A UPS cargo plane crashed shortly after takeoff from Louisville Muhammad Ali International Airport on Tuesday evening, federal officials said.
According to the Federal Aviation Administration, UPS Flight 2976 went down around 5:15 p.m. local time after departing the airport. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu.
IN CASE YOU MISSED IT | United flight lands safely at Reagan National after bomb threat
Flames and heavy smoke were seen rising from the airfield as fire crews worked to extinguish the blaze.
It’s not yet known whether there were any injuries or fatalities. The cause of the crash remains under investigation.
"This is an incredible tragedy that our community will never forget," said Louisville Mayor Craig Greenberg. "We are so thankful for our brave first responders who have flooded the scene to help try and control the fire and provide support for any victims on the ground.
IN CASE YOU MISSED IT | Weather balloon may have caused windshield crack on United plane
The FAA said both the agency and the National Transportation Safety Board will investigate.
The Louisville Muhammad Ali International Airport remains closed while crews continue firefighting and investigation efforts.