Nov 18, 2009 7:45 AM by Associated Press
The Food and Drug Administration say the stomach-soothing drug Prilosec lowers the effectiveness of Plavix by half. Plavix is marketed by Sanofi-Aventis and Bristol-Myers Squibb. It is the world's second-best selling drug with global sales of $8.6 billion last year.
Plavix can upset the stomach, so, it is often prescribed with acid-blocking drugs. The FDA says patients who need to reduce their stomach acid should take alternative drugs like Johnson & Johnson's Mylanta or Boehringer Ingelheim's Zantac.